ESM1|Endocan ELISA|Recombinant|Antibody

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Endothelial cell-Specific Molecule 1(ESM1)/Endocan (Human) ELISA, Endocan (Mouse) ELISA
Biomarker for Tumor and obesity
Alternative name: endocan endothelial-cell specific molecule-1
ESM1 is a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. ESM1 also is secreted adipokine. Circulating ESM-1 levels increased significantly, albeit modestly. ESM-1 is actively produced by adipocytes. However, since ESM-1 adipocyte gene expression and circulating plasma levels are not correlated, other sources of ESM-1 may be more important. Circulating ESM-1 levels are reduced in the overweight and obese, consistent with the notion that ESM-1 may play some role in obesity-associated vascular disease.
Human ESM1/Endocan ELISA Kit SK00318-06 had been used by Dr. Jing YY on following research paper. Serum endocan levels are correlated with the presence and severity of coronary artery disease in patients with hypertension. BACKGROUND: Endothelial dysfunction is one of the most important early indicators of atherosclerosis in hypertension (HT) patients. Endocan has been reported to play a role in the pathophysiology of endothelial dysfunction. OBJECTIVE: We sought to assess whether serum endocan levels are correlated with the presence and severity of coronary artery disease (CAD) in patients with HT. METHODS:We measured endocan levels in 164 patients with HT and in 55 controls. The severity of CAD was assessed by the coronary atherosclerosis index scores. RESULTS: Serum endocan levels were independently correlated with the presence and severity of CAD in HT patients. CONCLUSION:Endocan might function as a useful biomarker for monitoring the development and progression of CAD in HT patients. Wang XS, Yang W, Luo T, Wang JM, Jing YY. Genet Test Mol Biomarkers. 2015 Mar;19(3):124-7. doi: 10.1089/gtmb.2014.0274. Epub 2015 Jan 14.
New human ESM1 /Endocan ELISA Kit for serum and plasma samples assay



	Human ESM-1 /Endocan ELISA Code No.: SK00318-06 Size: 96 T Price: $460.00 USD Standard Range:3.125-200 ng/ml Sensitivity: 500 pg/ml Sample Type: serum, EDTA plasma Sample requres: pretreatment of samples IntraCV: 6-8% InterCV: 10-12% Protocol: PDF
	Human Endocan / ESM-1 ELISA Code No.: SK00318-01 Size: 96 T Price: $460.00 USD Standard Range:390-25000 pg/ml Dynamic Range: 390-25000 pg/ml Sensitivity: 98 pg/ml Sample Type: serum, EDTA plasma Sample requres: pretreatment of samples IntraCV: 6-8% InterCV: 10-12% Protocol: PDF
	Mouse ESM-1 /Endocan ELISA Kit Code No.: SK00318-19 Size: 96 T Price: $460.00 USD Standard Range:78 - 5000 pg/ml Sensitivity: 30 pg/ml Specificity: Mouse ESM1/Endocan (HEK293 cells derived 50 KD). BALB/C mouse serum can not be detected . Calibration: Mouse ESM1 derived from HEK293 (50KD) Sample Type: Serum,Urine, Cell cultures. Sample requres: 50 uL per well IntraCV: 6-8% InterCV: 10-12% Protocol: PDF
	Mouse ESM-1 /Endocan ELISA Kit Code No.: SK00318-04 Size: 96 T Price: $460.00 USD Standard Range:78 - 5000 pg/ml Sensitivity: 30 pg/ml Specificity: Mouse ESM1/Endocan (HEK293 cells derived 50 KD). BALB/C mouse serum can not be detected . Calibration: Mouse ESM1 derived from HEK293 (50KD) Sample Type: Serum,Urine, Cell cultures. Sample requres: 50 uL per well IntraCV: 6-8% InterCV: 10-12% Protocol: PDF
	Mouse ESM-1 ELISA Code No.: SK00318-09 Size: 96 T Price: $420.00 USD Standard Range:3.12 - 50 ng/ml Sensitivity: 1.8 ng/ml Calibration: Mouse ESM1 derived from HEK293 cells (50 KD) Specificity: Mouse ESM1 derived from HEK293 (50 KD) BALB/C Mouse Serum can not be detected. Sample Type: HEK293 cell cultures Sample requres: 50 uL per well IntraCV: 6-8% InterCV: 10-12% Protocol: PDF

	Anti Human Endocan/ESM1 Monoclonal Antibody Code No.: A00318-09-100 Size: 100 ug Price: $360.00 USD Host: Mice Antigen: human ESM1 Rec. Ab Type: Monoclonal Purification: Protein G Clone: 2B1F3G10 Applications: E, WB Working Dilution: WB: 2-4 ug/ml Data Sheet:PDF
	Anti Human ESM1 IgG Code No.: A00318-01-100 Size: 100 ug Price: $220.00 USD Host: Rabbit Antigen: human ESM1Rec. Ab Type: Polyclonal IgG Purification: Protein A Applications: E, IHC, WB Working Dilution: 2 ug/ml) Data Sheet: PDF
	Human ESM1 Recombinant Code No.: 00318-01-100 Size: 100 ug Price: $360.00 USD Protein ID:Q9NQ30 Gene ID: 11082 MW:20 KD (monomer), 40 KD (dimer) Tag: His Tag on N-Terminus Expressed: E. Coli Purity: 80% Data Sheet: PDF
	Anti Endocan/ESM1 (Mouse) IgG Code No.: A00318-10-100 Size: 100 ug Price: $360.00 USD Target Protein ID:Q9NQ30 Host: rabbit Antigen: recombinant mouse endocan Purification: Protein A Application: IHC, E, WB WB:24 KD (cell cultures), 56 KD (serum samples) Data Sheet: PDF

Name	Code No.	Size	Price ($)
Endothelial-cell Specific Molecule-1 (ESM-1) /Endocan (Human) ELISA Kit for serum or plasma	SK00318-06	96 T	460.00
Endothelial-cell Specific Molecule-1 (ESM-1)/Endocan (Human) ELISA Kit for serum or plasma	SK00318-01	96 T	460.00
ESM-1/Endocan (Mouse) ELISA Kit	SK00318-19	96 T	460.00
ESM-1/Endocan (Mouse) ELISA Kit	SK00318-04	96 T	460.00
ESM-1/Endocan (Mouse) ELISA Kit	SK00318-09	96 T	460.00
ESM-1/Endocan (Mouse) ELISA Kit	SK00318-03	96 T	inquire
Endocan / ESM1 (Human) (Human cells derived) recombinant	00318-11-05	5 ug	260.00
Endocan / ESM1 (Mouse) (Human cells derived) recombinant	00318-12-05	5 ug	260.00
ESM1 (Human) recombinant	00318-01-50	50 ug	250.00
ESM1 (Human) recombinant	00318-01-100	100 ug	360.00
Endocan / ESM1 (Mouse) recombinant	00318-12-50	50 ug	250.00
Endocan / ESM1 (Mouse) recombinant	00318-12-100	100 ug	360.00
Rabbit Anti ESM1 (Human) IgG	A00318-01-100	100 ug	220.00
Anti ESM1 (Human) Monoclonal IgG	A00318-02-100	100 ug	260.00
Anti ESM1 (Human) Monoclonal IgG	A00318-03-100	100 ug	260.00
Anti ESM1 (Human) Monoclonal IgG	A00318-04-100	100 ug	260.00
Anti ESM1 (Human) Monoclonal IgG	A00318-05-100	100 ug	260.00
Anti ESM1 (Human) Monoclonal IgG	A00318-06-100	100 ug	260.00
Anti ESM1 (Mouse) IgG	A00318-10-100	100 ug	260.00
Anti ESM1 (Mouse) IgG	A00318-10-50B	100 ug	320.00

New human ESM1 /Endocan ELISA Kit for serum and plasma samples assay